Drug Interactions with Common ED Prescription Medications
Work with your healthcare professional to find the right medicine and dosage for you. Before taking any medicine for erectile dysfunction, get your healthcare professional's OK.
Alternative Names
"How (not) to communicate new scientific information: a memoir of the famous Brindley lecture". Archived from the original on 2022-02-03. "The medicalisation of sex: a barrier to intercourse?". Archived from the original on 2023-12-13. "Role of Medical Anthropology in Understanding Cultural Differences in Sexuality".
Pulmonary hypertension
Cultural Differences and the Practice of Sexual Medicine. Archived from the original on 3 February 2022. "Prevalence of erectile dysfunction and its treatment in a Mexican population: distinguishing between erectile function change and dysfunction". "Erectile dysfunction in the community: trends over time in incidence, prevalence, GP consultation and medication use – the Krimpen study: trends in ED". "Bad Timing: The Problematics of Intimacy in On Chesil Beach". This includes supplements and herbal remedies you can get without a prescription. Some erectile dysfunction medicines might cause you harm if you: Take nitrate drugs such as nitroglycerin (Nitro-Dur, Nitrostat, others), cenforce 150mg tablets isosorbide mononitrate (Monoket) and isosorbide dinitrate (Isordil, Bidil).
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 60mg | 270 + 10 Pills | 443.96€ 422.82€ | |
| Kamagra Polo | 100 mg | 12 Pills | 60.21€ 57.34€ | |
| Levitra Original | 20mg | 12 Pills | 81.99€ 78.09€ | |
| Cialis Original | 20mg | 12 Pills | 78.32€ 74.59€ | |
| Kamagra | 100mg | 12 Pills | 55.64€ 52.99€ | |
| Cialis Super Active | 20mg | 30 + 6 Pills | 128.09€ 121.99€ | |
| Levitra Generic | 20mg | 30 + 4 Pills | 70.59€ 67.23€ | |
| Viagra Oral Jelly | 100mg | 30 + 5 Sachets | 115.76€ 110.25€ | |
| Viagra Generic | 25mg | 180 + 6 Pills | 154.93€ 147.55€ | |
| Levitra Generic | 40mg | 10 Pills | 41.37€ 39.40€ | |
| Kamagra Gold | 50 mg | 120 + 6 Pills | 281.13€ 267.74€ | |
| Levitra Generic | 60mg | 20 Pills | 81.30€ 77.43€ | |
| Viagra Generic | 50mg | 360 + 10 Pills | 225.33€ 214.60€ | |
| Levitra Generic | 60mg | 180 + 10 Pills | 501.43€ 477.55€ | |
| Cialis Generic | 10mg | 10 Pills | 31.41€ 29.91€ | |
| Cialis Original | 20mg | 8 Pills | 61.70€ 58.76€ |
Have very low blood pressure, called hypotension. You use a fine needle to put alprostadil (Caverject, Edex) into the base or side of your penis. The dose of each shot is for an erection lasting no longer than an hour.These shots may have one or two other medicines in them as well (BiMix,Tri-Mix).
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Archived from the original on 2021-10-09. ^ Enforcement Report for June 30, 2010 Archived June 25, 2016, at the Wayback Machine, United States Food and Drug Administration ^ Hidden Risks of Erectile Dysfunction "Treatments" Sold Online Archived 2019-04-23 at the Wayback Machine, United States Food and Drug Administration, February 21, 2009 ^ Lee HW, Lee MS, Kim TH, Alraek T, Zaslawski C, Kim JW, et al. Bonk: The Curious Coupling of Science and Sex. Trial by Impotence: Virility and Marriage in Pre-Revolutionary France. "Sexual behaviour and its medicalisation: in sickness and in health".
ED drugs and interaction with Nitroglycerin
Archived from the original on 2023-12-23. "The medicalization of sexuality: Conceptual, normative, and professional issues". "The history of the medicalisation of rapid ejaculation—A reflection of the rising importance of female pleasure in a phallocentric world". ^ Hoyland K, Vasdev N, Adshead J (2013). "The use of vacuum erection devices in erectile dysfunction after radical prostatectomy". Side effects can include mild bleeding from the shot site and an erection that lasts too long, called priapism. Rarely, fibrous tissue may form where you give yourself the shot.A member of your healthcare team shows you how to give yourself the shot. Because you use a very fine needle, pain from the shot most often is minor. The dose of each shot is for an erection lasting no longer than an hour. These shots may have one or two other medicines in them as well (BiMix,Tri-Mix). Rarely, fibrous tissue may form where you give yourself the shot.
- Penicillin: An antibiotic used to treat bacterial infections including syphilis and pneumonia.
- Amoxicillin: A broad-spectrum penicillin effective against ear, nose, throat, urinary tract infections.
- Ciprofloxacin: A fluoroquinolone used for urinary, respiratory, and gastrointestinal bacterial infections.
- Metronidazole: An antimicrobial for treating bacterial and parasitic infections like giardiasis and bacterial vaginosis.
- Doxycycline: A tetracycline antibiotic used for respiratory infections, Lyme disease, and acne.
- Ceftriaxone: A cephalosporin antibiotic for severe infections like meningitis and gonorrhea.
- Vancomycin: Used to treat serious Gram-positive infections, including MRSA.
- Azithromycin: A macrolide antibiotic for respiratory infections, chlamydia, and skin infections.
- Clindamycin: Effective against anaerobic bacteria and certain protozoal infections.
- Levofloxacin: A fluoroquinolone used for pneumonia, urinary tract infections, and skin infections.
- Trimethoprim-Sulfamethoxazole: Combines antibiotics for urinary tract infections and certain pneumonia cases.
A member of your healthcare team shows you how to give yourself the shot. This involves placing medicine inside your penis into the tube that carries urine from the body, called the urethra. You use a special applicator to put the medicine into the tip of your penis.
| Drug A | Drug B | Interaction Type | Effect |
|---|---|---|---|
| Sildenafil | Nitrates | Potent vasodilation | Hypotension |
| Tadalafil | Alpha-blockers | Additive blood pressure lowering | Dizziness, fainting |
| Vardenafil | CYP3A4 inhibitors | Increased drug levels | Prolonged side effects |
| Avanafil | Blood pressure medications | Increased hypotensive effect | Risk of sudden blood pressure drops |
The medicine increases blood flow to cause an erection.The erection most often starts within 10 minutes and lasts between 30 and 60 minutes. Side effects can include a burning feeling in the penis and minor bleeding in the urethra. The medicine increases blood flow to cause an erection. The erection most often starts within 10 minutes and lasts between 30 and 60 minutes. For those who have low levels of the hormone testosterone, testosterone replacement might help with erectile dysfunction. More commonly, you might use this with other treatments for erectile dysfunction.
30-Second Takeaway
This test uses sound waves to look at the blood vessels that send blood to the penis. It involves using a wandlike device called a transducer held over the blood vessels. It makes a video image that can show if you have blood flow problems.Healthcare professionals sometimes do this test after putting a shot of medicine into the penis to stimulate blood flow and make an erection. It makes a video image that can show if you have blood flow problems. Healthcare professionals sometimes do this test after putting a shot of medicine into the penis to stimulate blood flow and make an erection.
Does hair loss treatment cause erectile dysfunction?
Your healthcare professional may ask questions to screen for depression and other mental issues that can cause erectile dysfunction. Treatment for erectile dysfunction depends on the cause of your erectile dysfunction, how bad it is and whether you have underlying health conditions. Your healthcare professional can tell you the pros and cons of each treatment. What your partner wants also might be part of your treatment choices. Medicines taken by mouth work for many people who have erectile dysfunction. It draws blood into the penis to make an erection. Placing a rubber ring around the base of the ceridaviescampaigner co uk penis helps keep the erection. If medicines don't work for you or aren't right for you, your healthcare professional might suggest other treatment.
What Are Alternative Treatments for Erectile Dysfunction?
These medicines won't improve sex for them. The medicines vary in dosage, how long they work and side effects. Possible side effects include flushing, stuffy nose, headache, vision changes, backache and stomach upset. These medicines might not work right away. They might work less well after prostate surgery and for people who have diabetes and other conditions. A penis pump, also called a vacuum erection device, is a plastic tube that fits over the penis. A hand or battery-powered pump attaches to the tube. The pump sucks air out of the tube. This makes a vacuum that pulls blood into your penis.Once you get an erection, you put a rubber tension ring around the base of your penis. This holds in the blood and helps you keep the erection. You then remove the vacuum device.The erection most often lasts long enough to have sex. You remove the tension ring after sex. Your penis may bruise, and the band might weaken ejaculation. Your penis might feel cold to the touch.If a penis pump works well for you, your healthcare professional might suggest or prescribe a certain model. That way you can be sure it's right for you and made by a company you can trust. This makes a vacuum that pulls blood into your penis. Once you get an erection, you put a rubber tension ring around the base of your penis. The erection most often lasts long enough to have sex. If a penis pump works well for you, your healthcare professional might suggest or prescribe a certain model. This treatment involves surgery to place an implant into the penis. You can inflate some of these devices, which lets you control when and how long you have an erection.
- Onset of action: How quickly a drug starts to work after administration.
- Duration of action: How long the drug's effects are expected to last.
- Half-life: The time it takes for the drug's concentration to reduce by half.
- Bioavailability: The proportion of the drug that enters circulation when introduced.
- Peak plasma time: The time it takes to reach the maximum concentration in the blood.
- Metabolism: How the drug is broken down, primarily by liver enzymes like CYP3A4.
- Excretion: How the drug is eliminated from the body, usually via urine or feces.
- Storage conditions: Most ED medications are stored at room temperature away from light.
- expiration date: The date after which the drug should not be used.
- Proper disposal: How to safely discard unused or expired medications.
But you can bend it away from the body for sex and toward the body when you don't want it to show.Healthcare professionals don't often suggest penile implants until you've tried other erectile dysfunction treatments first. People who have tried other therapies without success tend to be happy with their implants.As with any surgery, there's a risk of complications, such as infection. Your healthcare professional might delay surgery if you have a urinary tract or other type of infection. But you can bend it away from the body for sex and toward the body when you don't want it to show. Healthcare professionals don't often suggest penile implants until you've tried other erectile dysfunction treatments first.
Segmental Overview
These medicines relax muscles in the penis. They increase blood flow in response to sexual stimulation. These pills alone don't cause an erection. But they can make it easier for you to get an erection with sexual stimulation. People who can get and keep erections without help don't need erectile dysfunction medicines. People who have tried other therapies without success tend to be happy with their implants. Maybe stress, anxiety or depression causes your erectile dysfunction or the condition makes stress and issues with your partner.
- Vacuum pump types: Include manual pumps, battery-operated pumps, and FDA-cleared devices.
- Constriction ring materials: Made from silicone, leather, or metal; must be timed.
- Pump sizing: Important to choose the correct cylinder size for effective use.
- Implant surgery: Procedure typically takes 1-2 hours under general or spinal anesthesia.
- Implant recovery: Involves several weeks of healing and learning to use the device.
- Implant risks: Include infection, mechanical failure, and erosion, though rare.
- Implant satisfaction: Has very high patient and partner satisfaction rates.
- Malleable implants: Rods that keep the penis permanently firm but bendable.
- Inflatable implants: Allow for a flaccid state and an erect state via a pump.
- Three-piece inflatable implants: Include cylinders, a pump, and a fluid reservoir.
Then your healthcare professional may suggest that you, or you and your partner, see a counselor. There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form.
| Drug Name | Active Ingredient | Brand Name | Typical Dosage |
|---|---|---|---|
| Viagra | Sildenafil citrate | Viagra | 50 mg, 100 mg |
| Cialis | Tadalafil | Cialis | 10 mg, 20 mg |
| Levitra | Vardenafil | Levitra | 10 mg, 20 mg |
| Stendra | Avanafil | Stendra | 50 mg, 100 mg |
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What special precautions should I follow?
Archived from the original on 19 October 2021. Sexually Transmitted Disease: An Encyclopedia of Diseases, Prevention, Treatment and Issues. "Implants, Mechanical Devices, and Vascular Surgery for Erectile Dysfunction". Urologist Tobias Kohler, M.D., answers the most frequently asked questions about erectile dysfunction. Diagnosing erectile dysfunction involves having a physical exam and answering questions about your medical and sexual history.
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If you have ongoing health conditions that could be involved, you might need other tests. Or you vardenafil 10 mg tablet might need to see a specialist. This might involve an exam of your penis and testicles and checking for nerve damage. A sample of your blood sent to a lab can check for signs of heart disease, diabetes, low testosterone levels and other health conditions. Like blood tests, urine tests can show signs of diabetes and other health conditions. We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices. You may opt out of email communications at any time by clicking on the unsubscribe link in the email. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Please, try again in a couple of minutes For many people, lifestyle choices cause erectile dysfunction or make it worse.
| Population | Considerations | Approved Usage | Notes |
|---|---|---|---|
| Elderly Men | Increased risk of side effects | Yes | Dose adjustments may be needed |
| Men with Diabetes | May require higher doses | Yes, with caution | Monitor for cardiovascular effects |
| Men on Heart Medication | Risk of interactions | Yes, but caution needed | Consult healthcare provider |
| Post-prostatectomy | Reduced efficacy possible | Often used with counseling | Tailored treatment needed |